Title: An Introduction to All of Us — The Precision Medicine Initiative: Anything but clinical research as usual
Presented: February 23, 2017
About the presenter:
Dr. Steven Steinhubl is an Associate Professor of Genomic Medicine at The Scripps Research Institute, a cardiologist at Scripps Health, and the Director of Digital Medicine at the Scripps Translational Science Institute. The mission of the Digital Health Division of STSI is to guide innovation and the transformation of clinical research as well as clinical care that has been made possible through the availability of digital technologies. Dr. Steinhubl’s research activities have covered a broad range of topics in the treatment and prevention of cardiovascular disease, the application of integrated systems-based approaches to the optimal identification, communication and treatment of individualized risk, and most recently the clinical implementation of mobile health technologies and associated data analytics.
He has been the principal investigator or helped lead dozens of large-scale randomized trials and has authored over 200 peer-reviewed manuscripts as well as numerous book chapters. For the past two years he has been on the faculty of the mHealth Summer Training Institute.
About the presentation:
The promise of the All of Us (formally known as the Precision Medicine Initiative Cohort Program – PMI-CP) rests on the capacity to recruit, measure, and engage participants at unprecedented scale. It’s aim is to include people representing all ancestries, all common medical conditions, and to enroll an exponentially greater number of participants than in any previous large cohort studies represents a grand leap forward in our approach to understanding human health. Our ability to gather individualized, granular data – a panoramic composite of clinical records, genomic data, and other biologic samples, and participant-generated data via biosensors and self-reported outcomes will further distinguish All of Us from earlier or similar ongoing research efforts. For the All of Us Program to be sustainable, traditional views of the researcher-participant relationship need to be brought into the modern era where individual participants can access their data, use it to enable their own health choices, and voluntarily contribute it to an aggregate commons to benefit society at large. In additional, to be of greatest value to society, the Program needs to be built on a platform of open science such that all researchers – from tenured academicians to citizen scientists – are empowered to participate.
All of Us is designed to be transformational, as both a research resource and as a model for the future of clinical care. Accomplishing this will require the input and collaboration from everyone interested in changing health and healthcare.